Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis.
第一作者:
Cathryn A,Broderick
第一单位:
Division of Molecular Therapy, Institute of Ophthalmology, University College, London, 11-43 Bath Street, London EC1V 9EL, UK.
作者:
主题词
动物(Animals);自身免疫疾病(Autoimmune Diseases);依赖病毒(Dependovirus);女(雌)性(Female);遗传载体(Genetic Vectors);白细胞介素10(Interleukin-10);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);单核细胞(Monocytes);光感受器细胞, 脊椎动物(Photoreceptor Cells, Vertebrate);视网膜变性(Retinal Degeneration);葡萄膜炎(Uveitis)
DOI
10.1016/j.ymthe.2005.03.018
PMID
16043105
发布时间
2012-11-15
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Molecular therapy
369-73页
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