Dissolution mechanism of poorly water-soluble drug from extended release solid dispersion system with ethylcellulose and hydroxypropylmethylcellulose.
第一作者:
Toshio,Ohara
第一单位:
Analytical Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., 2-1-6 Kashima, Osaka 532-8514, Japan. toshio.ohara@jp.astellas.com
作者:
主题词
消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);纤维素(Cellulose);迟效制剂(Delayed-Action Preparations);氢离子浓度(Hydrogen-Ion Concentration);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);吲哚美辛(Indomethacin);甲基纤维素(Methylcellulose);显微镜检查, 电子, 扫描(Microscopy, Electron, Scanning);粉剂(Powders);溶解度(Solubility);谱学, 傅里叶变换红外(Spectroscopy, Fourier Transform Infrared);水(Water);X线衍射(X-Ray Diffraction)
DOI
10.1016/j.ijpharm.2005.06.019
PMID
16102924
发布时间
2016-11-24
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