A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma.
作者:
主题词
细胞低氧(Cell Hypoxia);细胞系, 肿瘤(Cell Line, Tumor);抗药性, 肿瘤(Drug Resistance, Neoplasm);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);免疫沉淀法(Immunoprecipitation);MAP激酶信号系统(MAP Kinase Signaling System);丝裂原激活蛋白激酶激酶类(Mitogen-Activated Protein Kinase Kinases);神经母细胞瘤(Neuroblastoma);蛋白质类(Proteins);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);转录因子(Transcription Factors);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子受体1(Vascular Endothelial Growth Factor Receptor-1)
DOI
10.1158/0008-5472.CAN-04-4575
PMID
16103078
发布时间
2009-11-19
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Cancer research
7267-75页
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