XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells.
第一作者:
Boaz,Tirosh
第一单位:
Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
作者:
主题词
动物(Animals);细胞分化(Cell Differentiation);细胞系(Cell Line);CpG岛(CpG Islands);DNA结合蛋白质类(DNA-Binding Proteins);内质网(Endoplasmic Reticulum);基因表达调控(Gene Expression Regulation);糖蛋白类(Glycoproteins);组织相容性抗原Ⅰ类(Histocompatibility Antigens Class I);免疫球蛋白轻链(Immunoglobulin Light Chains);免疫球蛋白μ链(Immunoglobulin mu-Chains);脂多糖类(Lipopolysaccharides);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);核蛋白质类(Nuclear Proteins);浆细胞(Plasma Cells);蛋白质生物合成(Protein Biosynthesis);蛋白质转运(Protein Transport);RNA, 信使(RNA, Messenger);受体, 抗原, T细胞, α-β(Receptors, Antigen, T-Cell, alpha-beta);转录因子(Transcription Factors)
DOI
10.1084/jem.20050575
PMID
16103408
发布时间
2018-11-13
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