Epidermal growth factor receptor acts as a negative regulator for bacterium nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via an Src-dependent p38 mitogen-activated protein kinase signaling pathway.
第一作者:
Fumi,Mikami
第一单位:
Gonda Department of Cell and Molecular Biology, House Ear Institute, University of Southern California, Los Angeles 90057, USA.
作者:
主题词
动物(Animals);印迹法, 蛋白质(Blotting, Western);细胞黏附(Cell Adhesion);细胞分化(Cell Differentiation);细胞运动(Cell Movement);减量调节(Down-Regulation);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);表皮生长因子(Epidermal Growth Factor);上皮细胞(Epithelial Cells);基因表达调控(Gene Expression Regulation);流感嗜血菌(Haemophilus influenzae);人类(Humans);免疫系统(Immune System);免疫沉淀法(Immunoprecipitation);MAP激酶激酶3(MAP Kinase Kinase 3);MAP激酶激酶6(MAP Kinase Kinase 6);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);模型, 生物学(Models, Biological);磷酰化(Phosphorylation);质粒(Plasmids);RNA干扰(RNA Interference);RNA, 信使(RNA, Messenger);重组蛋白质类(Recombinant Proteins);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);时间因素(Time Factors);Toll样受体2(Toll-Like Receptor 2);转染(Transfection);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases);src族激酶类(src-Family Kinases)
DOI
10.1074/jbc.M503941200
PMID
16115866
发布时间
2021-02-09
- 浏览19
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文