Increase of C1q biosynthesis in brain microglia and macrophages during lentivirus infection in the rhesus macaque is sensitive to antiretroviral treatment with 6-chloro-2',3'-dideoxyguanosine.
第一作者:
Candan,Depboylu
第一单位:
Department of Molecular Neuroscience, Institute of Anatomy and Cell Biology, Philipps University, Robert-Koch-Str. 8, 35033 Marburg, Germany.
作者:
主题词
艾滋病痴呆复合征(AIDS Dementia Complex);动物(Animals);抗逆转录病毒药(Anti-Retroviral Agents);脑(Brain);补体C1q(Complement C1q);双脱氧核苷类(Dideoxynucleosides);疾病模型, 动物(Disease Models, Animal);脑炎(Encephalitis);慢病毒感染(Lentivirus Infections);猕猴(Macaca mulatta);巨噬细胞(Macrophages);小神经胶质细胞(Microglia);猴获得性免疫缺陷综合征(Simian Acquired Immunodeficiency Syndrome);增量调节(Up-Regulation);病毒载量(Viral Load)
DOI
10.1016/j.nbd.2005.01.030
PMID
16137563
发布时间
2006-11-15
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