换一批Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.
第一作者：
Florence,Joannard
第一单位：
INSERM UMR 620, Faculté de Pharmacie, Université Rennes 1, 2 av Prof Léon Bernard, 35043 Rennes Cedex, France.
作者：
医学主题词
动物(Animals);印迹法, RNA(Blotting, Northern);丁二烯类(Butadienes);细胞, 培养的(Cells, Cultured);细胞色素P450 CYP2B1(Cytochrome P-450 CYP2B1);二氯核糖呋喃苯丙咪唑(Dichlororibofuranosylbenzimidazole);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物协同作用(Drug Synergism);酶激活(Enzyme Activation);酶抑制剂(Enzyme Inhibitors);基因表达(Gene Expression);肝细胞(Hepatocytes);咪唑类(Imidazoles);荧光素酶类, 萤火虫(Luciferases, Firefly);男(雄)性(Male);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);突变(Mutation);腈类(Nitriles);苯巴比妥(Phenobarbital);磷酰化(Phosphorylation);吡啶类(Pyridines);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);转染(Transfection);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1016/j.toxlet.2005.08.006
PMID
16154717
发布时间
2016-11-24
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Toxicology letters
61-72页
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