Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen.
第一作者:
Arunashree,Bhamidipati
第一单位:
Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California 94143, USA.
作者:
医学主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);结合部位(Binding Sites);羧肽酶类(Carboxypeptidases);载体蛋白质类(Carrier Proteins);组织蛋白酶A(Cathepsin A);内质网(Endoplasmic Reticulum);糖蛋白类(Glycoproteins);人类(Humans);外源凝集素类(Lectins);分子序列数据(Molecular Sequence Data);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation);蛋白质折叠(Protein Folding);重组融合蛋白质类(Recombinant Fusion Proteins);酿酒酵母蛋白质类(Saccharomyces cerevisiae Proteins);序列比对(Sequence Alignment);四氢叶酸脱氢酶(Tetrahydrofolate Dehydrogenase)
DOI
10.1016/j.molcel.2005.07.027
PMID
16168370
发布时间
2012-07-10
- 浏览10
Molecular cell
741-51页
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