Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.

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作者： Bodour,Salhia ^[1] ; Frederieke,Rutten ; Mitsutoshi,Nakada ; Christian,Beaudry ; Michael,Berens ; Allison,Kwan ; James T,Rutka

作者单位： The Arthur and Sonia Labatt Brain Tumour Research Center and Division of Neurosurgery, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada. ^[1]

主题词肌动蛋白类(Actins);酰胺类(Amides);星形细胞瘤(Astrocytoma);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);酶激活(Enzyme Activation);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);溶血磷脂素类(Lysophospholipids);突变(Mutation);肿瘤侵润(Neoplasm Invasiveness);磷酰化(Phosphorylation);蛋白激酶抑制剂(Protein Kinase Inhibitors);吡啶类(Pyridines);转染(Transfection);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein);rho相关激酶类(rho-Associated Kinases)

DOI 10.1158/0008-5472.CAN-05-0160

PMID 16204049

发布时间 2021-12-03

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Cancer research

2005年65卷19期

8792-800页

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Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.

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Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.

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