换一批Immunogenicity and protective efficacy of Bacillus anthracis poly-gamma-D-glutamic acid capsule covalently coupled to a protein carrier using a novel triazine-based conjugation strategy.
第一作者：
Joseph,Joyce
第一单位：
Department of Vaccine and Biologics Research, Laboratory of Science and Investigative Toxicology and Bioprocess and Bioanalytical Research, Merck Research Laboratories, West Point, Pennsylvania 19486, USA. joseph.joyce@merck.com
作者：
医学主题词
动物(Animals);炭疽菌苗(Anthrax Vaccines);抗原, 细菌(Antigens, Bacterial);炭疽芽孢杆菌(Bacillus anthracis);细菌荚膜(Bacterial Capsules);生物物理学现象(Biophysical Phenomena);生物物理学(Biophysics);碳化二亚胺类(Carbodiimides);圆二色性(Circular Dichroism);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);谷氨酸(Glutamic Acid);氢离子浓度(Hydrogen-Ion Concentration);光(Light);磁共振波谱学(Magnetic Resonance Spectroscopy);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);吗啉类(Morpholines);肽类(Peptides);聚谷氨酸(Polyglutamic Acid);聚合物(Polymers);蛋白质结合(Protein Binding);季胺类化合物(Quaternary Ammonium Compounds);散射, 辐射(Scattering, Radiation);孢子, 细菌(Spores, Bacterial);巯基化合物(Sulfhydryl Compounds);温度(Temperature);时间因素(Time Factors);三嗪类(Triazines)
DOI
10.1074/jbc.M509432200
PMID
16293624
发布时间
2021-02-09
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