换一批
换一批A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors.
作者：
主题词
投药, 鼻内(Administration, Intranasal);动物(Animals);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);癌症疫苗(Cancer Vaccines);细胞系, 肿瘤(Cell Line, Tumor);细胞移植(Cell Transplantation);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);人乳头瘤病毒16(Human papillomavirus 16);免疫, 黏膜(Immunity, Mucosal);白细胞介素12(Interleukin-12);乳乳球菌(Lactococcus lactis);小鼠(Mice);鼻黏膜(Nasal Mucosa);肿瘤移植(Neoplasm Transplantation);癌基因蛋白质类, 病毒性(Oncogene Proteins, Viral);乳头瘤病毒E7蛋白质类(Papillomavirus E7 Proteins);乳头状瘤病毒感染(Papillomavirus Infections);乳头状瘤病毒疫苗(Papillomavirus Vaccines);重组蛋白质类(Recombinant Proteins);肿瘤病毒感染(Tumor Virus Infections);宫颈肿瘤(Uterine Cervical Neoplasms);病毒疫苗(Viral Vaccines)
DOI
10.4049/jimmunol.175.11.7297
PMID
16301635
发布时间
2019-05-16
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