换一批TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk.
第一作者：
Edward K,Chow
第一单位：
Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA 90095, USA.
作者：
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);抗原, 分化(Antigens, Differentiation);细胞系(Cell Line);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);CpG岛(CpG Islands);干扰素Ⅰ型(Interferon Type I);白细胞介素1受体相关激酶类(Interleukin-1 Receptor-Associated Kinases);肾小球系膜细胞(Mesangial Cells);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);髓样分化因子88(Myeloid Differentiation Factor 88);NF-κB(NF-kappa B);磷酸转移酶类(醇族体)(Phosphotransferases (Alcohol Group Acceptor));聚肌胞苷酸(Poly I-C);原癌基因蛋白质c-sis(Proto-Oncogene Proteins c-sis);RNA, 信使(RNA, Messenger);受体, 免疫(Receptors, Immunologic);信号传导(Signal Transduction);Smad4蛋白质(Smad4 Protein);Smad7蛋白质(Smad7 Protein);Toll样受体(Toll-Like Receptors);转化生长因子β(Transforming Growth Factor beta);转化生长因子β1(Transforming Growth Factor beta1);增量调节(Up-Regulation)
DOI
10.1038/sj.emboj.7600867
PMID
16308570
发布时间
2022-03-17
基金项目
GM07185/GM/NIGMS NIH HHS/United States
R01 CA087924/CA/NCI NIH HHS/United States
T32 GM007185/GM/NIGMS NIH HHS/United States
R01 AI056154/AI/NIAID NIH HHS/United States
R01 CA87924/CA/NCI NIH HHS/United States
T32 AI060567/AI/NIAID NIH HHS/United States
- 浏览7
The EMBO journal
4071-81页
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