Fusion of the human immunodeficiency virus type 1 tat protein transduction domain to thymidine kinase increases bystander effect and induces enhanced tumor killing in vivo.
第一作者:
Ennio,Tasciotti
第一单位:
Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology, 34012 Trieste, Italy.
作者:
主题词
动物(Animals);旁观者效应(Bystander Effect);疾病模型, 动物(Disease Models, Animal);基因产物, tat(Gene Products, tat);基因转移技术(Gene Transfer Techniques);基因, 转基因, 自杀(Genes, Transgenic, Suicide);HIV-1(HIV-1);人类(Humans);黑色素瘤(Melanoma);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 裸(Mice, Nude);肿瘤移植(Neoplasm Transplantation);肉瘤, 卡波西(Sarcoma, Kaposi);胸苷激酶(Thymidine Kinase);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);tat基因产物, 人免疫缺陷病毒(tat Gene Products, Human Immunodeficiency Virus)
DOI
10.1089/hum.2005.16.1389
PMID
16390270
发布时间
2012-11-15
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Human gene therapy
1389-403页
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