N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells.
第一作者:
H-J,Kim
第一单位:
Department of Thoracic/Head and Neck Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.
作者:
主题词
抗致癌药(Anticarcinogenic Agents);抗氧化剂(Antioxidants);细胞凋亡(Apoptosis);癌, 鳞状细胞(Carcinoma, Squamous Cell);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞色素c类(Cytochromes c);酶激活(Enzyme Activation);酶抑制剂(Enzyme Inhibitors);芬维A铵(Fenretinide);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);磷酰化(Phosphorylation);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases);蛋白激酶C(Protein Kinase C);原癌基因蛋白质c-jun(Proto-Oncogene Proteins c-jun);活性氧(Reactive Oxygen Species);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1038/sj.onc.1209303
PMID
16407847
发布时间
2018-11-13
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Oncogene
2785-94页
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