Selection and optimization of proteolytically stable llama single-domain antibody fragments for oral immunotherapy.
第一作者:
M M,Harmsen
第一单位:
Institute for Animal Science and Health (ID-Lelystad) of Wageningen University and Research Centre, Edelhertweg 15, 8219 PH, Lelystad, The Netherlands. michiel.harmsen@wur.nl
作者:
主题词
投药, 口服(Administration, Oral);氨基酸序列(Amino Acid Sequence);动物(Animals);抗原, 细菌(Antigens, Bacterial);骆驼, 新大陆(Camelids, New World);DNA改组(DNA Shuffling);大肠杆菌(Escherichia coli);大肠杆菌感染(Escherichia coli Infections);纤毛, 细菌(Fimbriae, Bacterial);胃肠内容物(Gastrointestinal Contents);免疫球蛋白碎片(Immunoglobulin Fragments);免疫疗法(Immunotherapy);分子序列数据(Molecular Sequence Data);肽水解酶类(Peptide Hydrolases);肽库(Peptide Library);蛋白质结构, 三级(Protein Structure, Tertiary);重组蛋白质类(Recombinant Proteins);序列比对(Sequence Alignment);无特异性病原体有机物(Specific Pathogen-Free Organisms);猪(Swine)
DOI
10.1007/s00253-005-0300-7
PMID
16450109
发布时间
2006-08-22
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