Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.
第一作者:
Ayyakannu,Ayyanan
第一单位:
Swiss Institute for Experimental Cancer Research, National Center of Competence in Research in Molecular Oncology, 155 Chemin des Boveresses, CH-1066 Epalinges/Lausanne, Switzerland.
作者:
医学主题词
动物(Animals);乳房(Breast);乳腺肿瘤(Breast Neoplasms);细胞转化, 肿瘤(Cell Transformation, Neoplastic);细胞, 培养的(Cells, Cultured);DNA损伤(DNA Damage);上皮细胞(Epithelial Cells);女(雌)性(Female);人类(Humans);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);RNA, 信使(RNA, Messenger);RNA, 肿瘤(RNA, Neoplasm);受体, Notch(Receptors, Notch);信号传导(Signal Transduction);Wnt1蛋白质(Wnt1 Protein)
DOI
10.1073/pnas.0600065103
PMID
16501043
发布时间
2022-03-18
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