Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter.
第一作者:
J,Ying
作者:
主题词
癌(Carcinoma);细胞系, 肿瘤(Cell Line, Tumor);染色体, 人, 4对(Chromosomes, Human, Pair 4);DNA甲基化(DNA Methylation);基因沉默(Gene Silencing);人类(Humans);淋巴瘤(Lymphoma);丝裂原活化蛋白激酶10(Mitogen-Activated Protein Kinase 10);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);启动区, 遗传(Promoter Regions, Genetic);蛋白质酪氨酸磷酸酶, 非受体13型(Protein Tyrosine Phosphatase, Non-Receptor Type 13);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);敏感性与特异性(Sensitivity and Specificity);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
DOI
10.1038/sj.leu.2404193
PMID
16572203
发布时间
2022-03-11
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Leukemia
1173-5页
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