换一批
换一批Discovery, structure-activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity.
第一作者：
Takashi,Yamamoto
第一单位：
Pharmaceutical Research Laboratory, Ajinomoto company Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Japan.
作者：
主题词
投药, 口服(Administration, Oral);动物(Animals);行为, 动物(Behavior, Animal);钙通道阻滞药(Calcium Channel Blockers);钙通道, N型(Calcium Channels, N-Type);细胞系, 肿瘤(Cell Line, Tumor);赛庚啶(Cyproheptadine);药物设计(Drug Design);药物评价, 临床前(Drug Evaluation, Preclinical);甲醛(Formaldehyde);豚鼠(Guinea Pigs);人类(Humans);男(雄)性(Male);分子结构(Molecular Structure);疼痛(Pain);疼痛测定(Pain Measurement);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 组胺(Receptors, Histamine);受体, 血清素(Receptors, Serotonin);立体异构现象(Stereoisomerism);构效关系(Structure-Activity Relationship);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1016/j.bmc.2006.03.040
PMID
16616501
发布时间
2014-11-20
- 浏览11
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
