Characterization of biodegradable chitosan microspheres containing vancomycin and treatment of experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus with prepared microspheres.
作者:
主题词
动物(Animals);抗菌药(Anti-Bacterial Agents);生物降解, 环境(Biodegradation, Environmental);壳聚糖(Chitosan);集落计数, 微生物(Colony Count, Microbial);疾病模型, 动物(Disease Models, Animal);药物调剂(Drug Compounding);药物植入物(Drug Implants);注射, 肌肉内(Injections, Intramuscular);男(雄)性(Male);甲氧西林抗药性(Methicillin Resistance);微球体(Microspheres);骨髓炎(Osteomyelitis);粒子大小(Particle Size);大鼠(Rats);大鼠, Wistar(Rats, Wistar);葡萄球菌感染(Staphylococcal Infections);金黄色葡萄球菌(Staphylococcus aureus);万古霉素(Vancomycin)
DOI
10.1016/j.ijpharm.2006.03.014
PMID
16624509
发布时间
2013-11-21
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