换一批Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring.
第一作者：
Todd W,Rockway
第一单位：
Infectious Disease Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 200 Abbott Park Road, Abbott Park, IL 60064-6217, USA. rockway@abbott.com
作者：
医学主题词
苯噻二嗪(Benzothiadiazines);酶抑制剂(Enzyme Inhibitors);基因型(Genotype);烃类, 芳香(Hydrocarbons, Aromatic);半数抑制浓度(Inhibitory Concentration 50);萘啶类(Naphthyridines);构效关系(Structure-Activity Relationship);病毒非结构蛋白质类(Viral Nonstructural Proteins);病毒复制(Virus Replication)
DOI
10.1016/j.bmcl.2006.04.022
PMID
16650984
发布时间
2022-01-10
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