JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis.
作者:
主题词
氨基酸取代(Amino Acid Substitution);动物(Animals);骨髓细胞(Bone Marrow Cells);女(雌)性(Female);基因表达调控(Gene Expression Regulation);基因表达调控, 病毒(Gene Expression Regulation, Viral);造血干细胞(Hematopoietic Stem Cells);人类(Humans);Janus激酶2(Janus Kinase 2);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);骨髓增殖性疾病(Myeloproliferative Disorders);真性红细胞增多症(Polycythemia Vera);聚合酶链反应(Polymerase Chain Reaction);原发性骨髓纤维化(Primary Myelofibrosis);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);原癌基因蛋白质类(Proto-Oncogene Proteins);逆转录病毒科(Retroviridae)
DOI
10.1182/blood-2006-02-002030
PMID
16670266
发布时间
2022-04-19
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Blood
1652-60页
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