N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption.
作者:
主题词
黏着连接(Adherens Junctions);动物(Animals);钙黏着糖蛋白类(Cadherins);癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞培养技术(Cell Culture Techniques);细胞运动(Cell Movement);细胞转化, 肿瘤(Cell Transformation, Neoplastic);囊肿(Cysts);酶激活(Enzyme Activation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);小鼠(Mice);突变(Mutation);肿瘤侵润(Neoplasm Invasiveness);神经细胞黏附分子类(Neural Cell Adhesion Molecules);癌基因蛋白质p21(ras)(Oncogene Protein p21(ras));胰腺管(Pancreatic Ducts);蛋白质结合(Protein Binding);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, 成纤维细胞生长因子, 2型(Receptor, Fibroblast Growth Factor, Type 2);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.1128/MCB.01055-05
PMID
16705170
发布时间
2024-04-12
- 浏览14

Molecular and cellular biology
4185-200页
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