Derivatives of Z-bisdehydrodoisynolic acid provide a new description of the binding-activity paradox and selective estrogen receptor modulator activity.
第一作者:
Molly,Adler
第一单位:
Department of Physiology, Southern Illinois University, Illinois 62901, USA.
作者:
医学主题词
醇类(Alcohols);酰胺类(Amides);结合, 竞争性(Binding, Competitive);药物设计(Drug Design);酯类(Esters);雌激素受体α(Estrogen Receptor alpha);雌激素受体β(Estrogen Receptor beta);基因表达(Gene Expression);人类(Humans);氢离子浓度(Hydrogen-Ion Concentration);菲类(Phenanthrenes);蛋白质结合(Protein Binding)
DOI
10.1210/en.2006-0316
PMID
16709609
发布时间
2007-11-14
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Endocrinology
3952-60页
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