Defective expression of HRK is associated with promoter methylation in primary central nervous system lymphomas.
作者:
主题词
细胞凋亡(Apoptosis);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);中枢神经系统肿瘤(Central Nervous System Neoplasms);周期素依赖激酶抑制剂p16(Cyclin-Dependent Kinase Inhibitor p16);周期素依赖激酶抑制剂p27(Cyclin-Dependent Kinase Inhibitor p27);DNA甲基化(DNA Methylation);无病生存(Disease-Free Survival);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);免疫组织化学(Immunohistochemistry);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);杂合子丢失(Loss of Heterozygosity);淋巴瘤(Lymphoma);O(6)-甲基鸟嘌呤DNA甲基转移酶(O(6)-Methylguanine-DNA Methyltransferase);启动区, 遗传(Promoter Regions, Genetic);视网膜母细胞瘤蛋白质(Retinoblastoma Protein);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);存活率分析(Survival Analysis);转录, 遗传(Transcription, Genetic);肿瘤抑制蛋白质p14ARF(Tumor Suppressor Protein p14ARF)
DOI
10.1159/000094322
PMID
16809940
发布时间
2011-11-17
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Oncology
212-21页
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