The antiepileptic drug topiramate preserves metabolism-secretion coupling in insulin secreting cells chronically exposed to the fatty acid oleate.
第一作者:
Francesca,Frigerio
第一单位:
Department of Cell Physiology and Metabolism, University Medical Centre, 1 rue Michel-Servet, CH-1211 Geneva 4, Switzerland.
作者:
医学主题词
动物(Animals);抗惊厥药(Anticonvulsants);肉碱O-软脂酰转移酶(Carnitine O-Palmitoyltransferase);细胞系(Cell Line);果糖(Fructose);基因表达调控(Gene Expression Regulation);胰岛素(Insulin);胰岛素分泌细胞(Insulin-Secreting Cells);膜电位(Membrane Potentials);线粒体膜(Mitochondrial Membranes);油酸(Oleic Acid);PPARα(PPAR alpha);RNA, 信使(RNA, Messenger);大鼠(Rats);甘油三酯类(Triglycerides)
DOI
10.1016/j.bcp.2006.07.013
PMID
16934763
发布时间
2018-12-17
- 浏览5
Biochemical pharmacology
965-73页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



