Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+.
作者:
主题词
3',5'-环AMP磷酸二酯酶类(3',5'-Cyclic-AMP Phosphodiesterases);氨基酸序列(Amino Acid Sequence);动物(Animals);结合部位(Binding Sites);COS细胞(COS Cells);钙(Calcium);钙信号(Calcium Signaling);细胞存活(Cell Survival);环核苷酸磷酸二酯酶类, 4型(Cyclic Nucleotide Phosphodiesterases, Type 4);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);磷脂酸类(Phosphatidic Acids);磷脂酶D(Phospholipase D);蛋白质结构, 二级(Protein Structure, Secondary);蛋白质转运(Protein Transport);重组融合蛋白质类(Recombinant Fusion Proteins);构效关系(Structure-Activity Relationship);毒胡萝卜内酯(Thapsigargin);高尔基体外侧网络(trans-Golgi Network)
DOI
10.1242/jcs.03106
PMID
16940352
发布时间
2022-01-29
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Journal of cell science
3799-810页
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