换一批
换一批Structural insights into autoreactive determinants in thyroid peroxidase composed of discontinuous and multiple key contact amino acid residues contributing to epitopes recognized by patients' autoantibodies.
作者：
主题词
动物(Animals);抗原, 表面(Antigens, Surface);自身抗体(Autoantibodies);自身免疫疾病(Autoimmune Diseases);结合部位, 抗体(Binding Sites, Antibody);CHO细胞(CHO Cells);克隆, 分子(Cloning, Molecular);仓鼠亚科(Cricetinae);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);表位作图(Epitope Mapping);表位(Epitopes);流式细胞术(Flow Cytometry);人类(Humans);成像, 三维(Imaging, Three-Dimensional);免疫显性表位(Immunodominant Epitopes);免疫球蛋白Fab片段(Immunoglobulin Fab Fragments);碘化物过氧化物酶(Iodide Peroxidase);模型, 分子(Models, Molecular);诱变, 定点(Mutagenesis, Site-Directed);突变蛋白质类(Mutant Proteins);甲状腺疾病(Thyroid Diseases);转染(Transfection)
DOI
10.1210/en.2006-0912
PMID
16959834
发布时间
2011-11-17
- 浏览46
Endocrinology
5995-6003页
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