换一批
换一批Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.
作者：
主题词
投药, 口服(Administration, Oral);动物(Animals);抗病毒药(Antiviral Agents);曲线下面积(Area Under Curve);结合部位(Binding Sites);生物利用度(Biological Availability);结晶学, X线(Crystallography, X-Ray);狗(Dogs);直鼻猴亚目(Haplorhini);肝炎病毒属(Hepacivirus);分子结构(Molecular Structure);脯氨酸(Proline);大鼠(Rats);构效关系(Structure-Activity Relationship);组织分布(Tissue Distribution);病毒非结构蛋白质类(Viral Nonstructural Proteins)
DOI
10.1021/jm060325b
PMID
17004721
发布时间
2014-11-20
- 浏览57
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
