换一批ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies.
第一作者：
Samuel,Hintermann
第一单位：
Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland.
作者：
医学主题词
动物(Animals);放射自显影术(Autoradiography);结合, 竞争性(Binding, Competitive);血蛋白质类(Blood Proteins);细胞系(Cell Line);化学现象(Chemical Phenomena);化学, 物理(Chemistry, Physical);仓鼠亚科(Cricetinae);兴奋性氨基酸激动剂(Excitatory Amino Acid Agonists);人类(Humans);指示剂和试剂(Indicators and Reagents);注射, 静脉内(Injections, Intravenous);配体(Ligands);男(雄)性(Male);质谱分析法(Mass Spectrometry);微粒体, 肝(Microsomes, Liver);肟类(Oximes);磷脂酰肌醇类(Phosphatidylinositols);正电子发射断层显像术(Positron-Emission Tomography);蛋白质结合(Protein Binding);吡啶类(Pyridines);使君子氨酸(Quisqualic Acid);放射性药物(Radiopharmaceuticals);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);大鼠, Wistar(Rats, Wistar);受体, 红藻氨酸(Receptors, Kainic Acid);组织分布(Tissue Distribution)
DOI
10.1016/j.bmc.2006.10.038
PMID
17110115
发布时间
2016-11-24
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