Lysophosphatidic acid downregulates tissue inhibitor of metalloproteinases, which are negatively involved in lysophosphatidic acid-induced cell invasion.
第一作者:
S,Sengupta
第一单位:
Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
作者:
医学主题词
动物(Animals);细胞运动(Cell Movement);上皮细胞(Epithelial Cells);女(雌)性(Female);GTP结合蛋白质α亚单位, Gi-Go(GTP-Binding Protein alpha Subunits, Gi-Go);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);溶血磷脂素类(Lysophospholipids);小鼠(Mice);肿瘤侵润(Neoplasm Invasiveness);肿瘤转移(Neoplasm Metastasis);卵巢肿瘤(Ovarian Neoplasms);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);金属蛋白酶类组织抑制剂(Tissue Inhibitor of Metalloproteinases);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1038/sj.onc.1210093
PMID
17130843
发布时间
2019-12-10
基金项目
R01 CA095042/CA/NCI NIH HHS/United States
- 浏览8
Oncogene
2894-901页
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