Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2).
作者:
主题词
细胞, 培养的(Cells, Cultured);趋化性, 白细胞(Chemotaxis, Leukocyte);色酮类(Chromones);糖原合成酶激酶3(Glycogen Synthase Kinase 3);人类(Humans);吗啉类(Morpholines);NFATC转录因子类(NFATC Transcription Factors);磷酰化(Phosphorylation);前列腺素D2(Prostaglandin D2);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, 免疫(Receptors, Immunologic);受体, 前列腺素(Receptors, Prostaglandin);信号传导(Signal Transduction);Th2细胞(Th2 Cells)
DOI
10.1016/j.bcp.2006.11.021
PMID
17196174
发布时间
2019-12-10
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Biochemical pharmacology
843-53页
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