Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway.
第一作者:
Shehla,Pervin
第一单位:
Departments of Obstetrics and Gynecology and Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA, USA.
作者:
医学主题词
烷基和芳基转移酶类(Alkyl and Aryl Transferases);乳腺肿瘤(Breast Neoplasms);细胞生长过程(Cell Growth Processes);细胞系, 肿瘤(Cell Line, Tumor);环GMP(Cyclic GMP);剂量效应关系, 药物(Dose-Response Relationship, Drug);真核细胞起始因子4E(Eukaryotic Initiation Factor-4E);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);一氧化氮(Nitric Oxide);亚硝基化合物(Nitroso Compounds);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);蛋白质生物合成(Protein Biosynthesis);蛋白激酶类(Protein Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);raf激酶类(raf Kinases)
DOI
10.1158/0008-5472.CAN-05-4623
PMID
17210710
发布时间
2021-12-03
- 浏览45
Cancer research
289-99页
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