换一批
换一批A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models.
作者：
主题词
投药, 口服(Administration, Oral);动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞增殖(Cell Proliferation);香豆素类(Coumarins);仓鼠亚科(Cricetinae);疾病模型, 动物(Disease Models, Animal);酶抑制剂(Enzyme Inhibitors);雌二醇(Estradiol);雌激素拮抗剂(Estrogen Antagonists);雌酮(Estrone);女(雌)性(Female);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);人类(Humans);白细胞(Leukocytes);甲基亚硝脲(Methylnitrosourea);分子结构(Molecular Structure);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 孕酮(Receptors, Progesterone);信号传导(Signal Transduction);甾醇硫酸酯酶(Steryl-Sulfatase);磺胺类(Sulfonamides);磺酸类(Sulfonic Acids);他莫昔芬(Tamoxifen);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1007/s10549-007-9495-x
PMID
17268815
发布时间
2015-11-19
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