Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.
第一作者:
Dwight V,Nissley
第一单位:
Basic Research Program, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.
作者:
医学主题词
圆二色性(Circular Dichroism);克隆, 分子(Cloning, Molecular);DNA, 病毒(DNA, Viral);HIV逆转录酶(HIV Reverse Transcriptase);HIV-1(HIV-1);模型, 分子(Models, Molecular);分子构象(Molecular Conformation);蛋白质构象(Protein Conformation);蛋白质亚单位(Protein Subunits);RNA, 病毒(RNA, Viral);重组蛋白质类(Recombinant Proteins);逆转录酶抑制剂(Reverse Transcriptase Inhibitors);酿酒酵母菌(Saccharomyces cerevisiae)
DOI
10.1042/BJ20061814
PMID
17286555
发布时间
2025-05-29
基金项目
N01 CO012400/CA/NCI NIH HHS/United States
R01 GM068406/GM/NIGMS NIH HHS/United States
R01 GM068406-01/GM/NIGMS NIH HHS/United States
N01-CO-12400/CO/NCI NIH HHS/United States
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