换一批
换一批Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodents.
作者：
主题词
酰胺类(Amides);动物(Animals);减肥药(Anti-Obesity Agents);结合, 竞争性(Binding, Competitive);体温(Body Temperature);体重(Body Weight);CHO细胞(CHO Cells);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);环AMP(Cyclic AMP);环己醇类(Cyclohexanols);剂量效应关系, 药物(Dose-Response Relationship, Drug);进食(Eating);人类(Humans);吲哚类(Indoles);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);分子结构(Molecular Structure);肥胖症(Obesity);哌啶类(Piperidines);吡啶类(Pyridines);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 大麻酚, CB1(Receptor, Cannabinoid, CB1);转染(Transfection)
DOI
10.1124/jpet.106.118737
PMID
17327489
发布时间
2017-11-16
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