Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts.
作者:
主题词
动物(Animals);骨髓细胞(Bone Marrow Cells);细胞分化(Cell Differentiation);共同培养技术(Coculture Techniques);剂量效应关系, 药物(Dose-Response Relationship, Drug);基因表达调控(Gene Expression Regulation);白细胞介素13(Interleukin-13);白细胞介素4(Interleukin-4);巨噬细胞(Macrophages);男(雄)性(Male);小鼠(Mice);NFATC转录因子类(NFATC Transcription Factors);成骨细胞(Osteoblasts);破骨细胞(Osteoclasts);骨保护素(Osteoprotegerin);RANK配体(RANK Ligand);RNA, 信使(RNA, Messenger);重组蛋白质类(Recombinant Proteins);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);STAT6转录因子(STAT6 Transcription Factor)
DOI
10.1111/j.1365-2567.2006.02538.x
PMID
17343616
发布时间
2018-11-13
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Immunology
573-9页
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