A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation.
作者:
主题词
乙酰化作用(Acetylation);腺苷三磷酸酶类(Adenosine Triphosphatases);细胞提取物(Cell Extracts);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);HCT116细胞(HCT116 Cells);HSP90热休克蛋白质类(HSP90 Heat-Shock Proteins);杂环化合物, 2环(Heterocyclic Compounds, 2-Ring);组蛋白酰基转移酶(Histone Acetyltransferases);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);组蛋白脱乙酰基酶类(Histone Deacetylases);组蛋白类(Histones);人类(Humans);免疫测定(Immunoassay);分子伴侣(Molecular Chaperones);蛋白质加工, 转译后(Protein Processing, Post-Translational)
DOI
10.1158/1535-7163.MCT-06-0496
PMID
17363504
发布时间
2020-09-30
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Molecular cancer therapeutics
1112-22页
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