HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation.
作者:
主题词
腺瘤, 肝细胞(Adenoma, Liver Cell);青少年(Adolescent);成年人(Adult);柠檬酸(Citric Acid);脂肪酸类(Fatty Acids);脂肪肝(Fatty Liver);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);糖原异生(Gluconeogenesis);糖酵解(Glycolysis);肝细胞核因子1α(Hepatocyte Nuclear Factor 1-alpha);人类(Humans);脂肪生成(Lipogenesis);肝(Liver);肝肿瘤(Liver Neoplasms);男(雄)性(Male);中年人(Middle Aged);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);启动区, 遗传(Promoter Regions, Genetic);反应元件(Response Elements);信号传导(Signal Transduction);胆固醇调节元件结合蛋白质1(Sterol Regulatory Element Binding Protein 1);转录因子(Transcription Factors)
DOI
10.1074/jbc.M610725200
PMID
17379603
发布时间
2021-02-09
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