Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival.
第一作者:
Emanuel F,Petricoin
第一单位:
Food and Drug Administration, Center for Biologics Evaluation and Research, Office of Cellular and Gene Therapy, National Cancer Institute, NIH, Bethesda, Maryland, USA.
作者:
主题词
动物(Animals);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);儿童(Child);儿童, 学龄前(Child, Preschool);无病生存(Disease-Free Survival);女(雌)性(Female);人类(Humans);婴儿(Infant);胰岛素受体底物蛋白质类(Insulin Receptor Substrate Proteins);男(雄)性(Male);小鼠(Mice);小鼠, SCID(Mice, SCID);磷蛋白类(Phosphoproteins);磷酰化(Phosphorylation);蛋白激酶类(Protein Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);横纹肌肉瘤(Rhabdomyosarcoma);信号传导(Signal Transduction);存活率(Survival Rate);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1158/0008-5472.CAN-06-1344
PMID
17409454
发布时间
2022-03-16
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Cancer research
3431-40页
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