换一批
换一批Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
作者：
主题词
腺苷三磷酸酶类(Adenosine Triphosphatases);动物(Animals);细胞凋亡(Apoptosis);细胞周期(Cell Cycle);细胞增殖(Cell Proliferation);结晶学, X线(Crystallography, X-Ray);抗药性, 肿瘤(Drug Resistance, Neoplasm);内皮细胞(Endothelial Cells);女(雌)性(Female);HCT116细胞(HCT116 Cells);HSP90热休克蛋白质类(HSP90 Heat-Shock Proteins);HT29细胞(HT29 Cells);人类(Humans);异恶唑类(Isoxazoles);小鼠(Mice);小鼠, 裸(Mice, Nude);NAD(P)H脱氢酶(醌)(NAD(P)H Dehydrogenase (Quinone));蛋白质结合(Protein Binding);吡唑类(Pyrazoles);治疗结果(Treatment Outcome);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1158/1535-7163.MCT-07-0149
PMID
17431102
发布时间
2020-09-30
- 浏览14
Molecular cancer therapeutics
1198-211页
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