Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.
第一作者:
Peter,Milberg
第一单位:
Department of Cardiology and Angiology, Hospital of the Westfälische Wilhelms-University, Münster, Germany. milbergp@uni-muenster.de
作者:
医学主题词
动作电位(Action Potentials);动物(Animals);抗心律失常药(Anti-Arrhythmia Agents);心律失常, 心性(Arrhythmias, Cardiac);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);心电描记术(Electrocardiography);电生理学技术, 心脏(Electrophysiologic Techniques, Cardiac);氟卡尼(Flecainide);心脏传导系统(Heart Conduction System);吡那地尔(Pinacidil);奎尼丁(Quinidine);兔(Rabbits);随机分配(Random Allocation);不应期, 电生理学(Refractory Period, Electrophysiological);索他洛尔(Sotalol);血管舒张药(Vasodilator Agents)
DOI
10.1111/j.1540-8167.2007.00813.x
PMID
17521304
发布时间
2014-11-20
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