Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice.
第一作者:
Todd W,Bauer
第一单位:
Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
作者:
主题词
动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);印迹法, RNA(Blotting, Northern);细胞分裂(Cell Division);细胞存活(Cell Survival);结直肠肿瘤(Colorectal Neoplasms);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);HT29细胞(HT29 Cells);人类(Humans);原位缺口末端标记(In Situ Nick-End Labeling);肝肿瘤, 实验性(Liver Neoplasms, Experimental);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);肿瘤移植(Neoplasm Transplantation);新生血管化, 病理性(Neovascularization, Pathologic);有机铂化合物(Organoplatinum Compounds);受体, IGF1型(Receptor, IGF Type 1);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1245/s10434-007-9486-5
PMID
17653802
发布时间
2018-12-01
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Annals of surgical oncology
2838-46页
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