A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses.
第一作者:
Daniel H,Sterman
第一单位:
Thoracic Oncology Gene Therapy Program and Abramson Family Cancer Research Institute, University of Pennsylvania Medical Center, Philadelphia, PA 19104-4283, USA. sterman@mail.med.upenn.edu
作者:
主题词
腺病毒科(Adenoviridae);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞因子类(Cytokines);女(雌)性(Female);氟脱氧葡萄糖F18(Fluorodeoxyglucose F18);基因转移技术(Gene Transfer Techniques);遗传载体(Genetic Vectors);人类(Humans);干扰素β(Interferon-beta);杀伤细胞, 天然(Killer Cells, Natural);男(雄)性(Male);间皮瘤(Mesothelioma);中年人(Middle Aged);胸腔积液, 恶性(Pleural Effusion, Malignant);胸膜肿瘤(Pleural Neoplasms);正电子发射断层显像术(Positron-Emission Tomography);放射性药物(Radiopharmaceuticals);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic)
DOI
10.1158/1078-0432.CCR-07-0403
PMID
17671130
发布时间
2021-01-03
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Clinical cancer research
4456-66页
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