换一批FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications.
第一作者：
Susan P,Whitman
第一单位：
Division of Hematology and Oncology, Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43240, USA. susan.whitman@osumc.edu
作者：
医学主题词
成年人(Adult);天冬氨酸(Aspartic Acid);细胞遗传学(Cytogenetics);无病生存(Disease-Free Survival);女(雌)性(Female);基因表达调控, 白血病(Gene Expression Regulation, Leukemic);人类(Humans);异亮氨酸(Isoleucine);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);预后(Prognosis);治疗结果(Treatment Outcome);fms样酪氨酸激酶3(fms-Like Tyrosine Kinase 3)
DOI
10.1182/blood-2007-08-107946
PMID
17940205
发布时间
2022-12-08
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Blood
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