Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling.
第一作者:
Yue-Zhen,Deng
第一单位:
Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
作者:
医学主题词
动物(Animals);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞黏附(Cell Adhesion);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);结缔组织生长因子(Connective Tissue Growth Factor);细胞周期蛋白D(Cyclin D);细胞周期蛋白类(Cyclins);食管肿瘤(Esophageal Neoplasms);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);即早蛋白质类(Immediate-Early Proteins);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);小鼠(Mice);小鼠, 裸(Mice, Nude);肿瘤转移(Neoplasm Metastasis);肿瘤移植(Neoplasm Transplantation);新生血管化, 病理性(Neovascularization, Pathologic);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);RNA干扰(RNA Interference);反应元件(Response Elements);信号传导(Signal Transduction);TCF转录因子类(TCF Transcription Factors);增量调节(Up-Regulation);β连环素(beta Catenin)
DOI
10.1074/jbc.M704141200
PMID
17951630
发布时间
2021-02-09
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