Transforming growth factor-beta (TGF- 1) down-regulates Notch3 in fibroblasts to promote smooth muscle gene expression.
第一作者:
Simone,Kennard
第一单位:
Vascular Biology Center and Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta, Georgia, 30912.
作者:
医学主题词
肌动蛋白类(Actins);动物(Animals);碱基序列(Base Sequence);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);牛(Cattle);细胞, 培养的(Cells, Cultured);减量调节(Down-Regulation);内皮细胞(Endothelial Cells);成纤维细胞(Fibroblasts);同源盒结构域蛋白质类(Homeodomain Proteins);小鼠(Mice);分子序列数据(Molecular Sequence Data);肌, 平滑(Muscle, Smooth);启动区, 遗传(Promoter Regions, Genetic);RNA, 小分子干扰(RNA, Small Interfering);受体, Notch1(Receptor, Notch1);受体, Notch(Receptors, Notch);信号传导(Signal Transduction);Smad3蛋白质(Smad3 Protein);Smad4蛋白质(Smad4 Protein);时间因素(Time Factors);转化生长因子β1(Transforming Growth Factor beta1);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1074/jbc.M706651200
PMID
17981798
发布时间
2022-03-18
- 浏览29
The Journal of biological chemistry
1324-1333页
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