Altered glycosylation of recombinant NKp30 hampers binding to heparan sulfate: a lesson for the use of recombinant immunoreceptors as an immunological tool.
第一作者:
Oren,Hershkovitz
第一单位:
The Shraga Segal Department of Microbiology and Immunology, Faculty of Health Sciences and the Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
作者:
主题词
动物(Animals);结合部位(Binding Sites);CHO细胞(CHO Cells);细胞系, 肿瘤(Cell Line, Tumor);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);糖基化(Glycosylation);硫酸乙酰肝素(Heparitin Sulfate);人类(Humans);自然细胞毒性触发受体3(Natural Cytotoxicity Triggering Receptor 3);肽-N4-(N-乙酰-β-葡糖胺)天冬酰胺酰胺酶(Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase);多糖类(Polysaccharides);受体, 免疫(Receptors, Immunologic);重组蛋白质类(Recombinant Proteins);光谱法, 质量, 基质辅助激光解吸电离(Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization)
DOI
10.1093/glycob/cwm125
PMID
18006589
发布时间
2008-11-21
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Glycobiology
28-41页
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