Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.

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第一作者： Keum-Jin,Yang

第一单位： Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Taejeon 301-131, South Korea.

作者： Keum-Jin,Yang ^[1] ; Sanghee,Shin ^[1] ; Longzhen,Piao ^[1] ; Eulsoon,Shin ^[1] ; Yuwen,Li ^[1] ; Kyeong Ah,Park ^[1] ; Hee Sun,Byun ^[1] ; Minho,Won ^[1] ; Janghee,Hong ^[1] ; Gi Ryang,Kweon ^[2] ; Gang Min,Hur ^[1] ; Jeong Ho,Seok ^[1] ; Taehoon,Chun ^[3] ; Derek P,Brazil ^[4] ; Brian A,Hemmings ^[5] ; Jongsun,Park ^[6]

作者单位： Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Taejeon 301-131, South Korea. ^[1] Department of Biochemistry, College of Medicine, Chungnam National University, Taejeon 301-131, South Korea. ^[2] Division of Biotechnology, School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, South Korea. ^[3] University College Dublin School of Biomolecular and Biomedical Science, University College Dublin Conway Institute, University College Dublin, Dublin 4, Ireland. ^[4] Friedrich Miescher Institute for Biomedical Research, Basel CH-4058, Switzerland. ^[5] Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, Taejeon 301-131, South Korea. Electronic address: insulin@cnu.ac.kr. ^[6]