A Novel iron-chelating derivative of the neuroprotective peptide NAPVSIPQ shows superior antioxidant and antineurodegenerative capabilities.
第一作者:
Dan,Blat
第一单位:
Department of Organic Chemistry and Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel.
作者:
主题词
动物(Animals);抗氧化剂(Antioxidants);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);正铁化合物(Ferric Compounds);亚铁化合物(Ferrous Compounds);人类(Humans);过氧化氢(Hydrogen Peroxide);羟肟酸类(Hydroxamic Acids);羟自由基(Hydroxyl Radical);铁螯合剂(Iron Chelating Agents);脂质过氧化作用(Lipid Peroxidation);男(雄)性(Male);神经保护药(Neuroprotective Agents);寡肽类(Oligopeptides);氧化性应激(Oxidative Stress);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley)
DOI
10.1021/jm070800l
PMID
18078312
发布时间
2014-11-20
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