Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.-论文-万方医学网

作者： Jeongwu,Lee ^[1] ; Myung Jin,Son ; Kevin,Woolard ; Nicholas M,Donin ; Aiguo,Li ; Chui H,Cheng ; Svetlana,Kotliarova ; Yuri,Kotliarov ; Jennifer,Walling ; Susie,Ahn ; Misuk,Kim ; Mariam,Totonchy ; Thomas,Cusack ; Chibawanye,Ene ; Hilary,Ma ; Qin,Su ; Jean Claude,Zenklusen ; Wei,Zhang ; Dragan,Maric ; Howard A,Fine

作者单位： Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. ^[1]

主题词动物(Animals);星形细胞(Astrocytes);骨形态发生蛋白受体, Ⅰ型(Bone Morphogenetic Protein Receptors, Type I);骨形态发生蛋白质类(Bone Morphogenetic Proteins);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);睫状神经营养因子(Ciliary Neurotrophic Factor);细胞因子类(Cytokines);DNA甲基化(DNA Methylation);DNA结合蛋白质类(DNA-Binding Proteins);后成说, 遗传(Epigenesis, Genetic);基因沉默(Gene Silencing);胶质母细胞瘤(Glioblastoma);人类(Humans);小鼠(Mice);小鼠, SCID(Mice, SCID);肿瘤干细胞(Neoplastic Stem Cells);磷酰化(Phosphorylation);启动区, 遗传(Promoter Regions, Genetic);STAT3转录因子(STAT3 Transcription Factor);转录因子(Transcription Factors)

DOI 10.1016/j.ccr.2007.12.005

PMID 18167341

发布时间 2019-10-03

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Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.

Cancer cell

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Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.

Cancer cell

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Cancer cell

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